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#1065 Functional Role of miR-196a in Neuroendocrine Tumor Cells
Introduction: An exclusive miRNA profiling of small intestinal neuroendocrine tumors (SI-NETs) was published in 2013; and nine miRNAs were selected for further investigations. We chose miR-196a to elucidate its target genes and biological functions, by using NET cells as in vitro models.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author:
Authors: Shi H, Li S, Khan M, Caplin M, Meyer T,
Keywords: neuroendocrine tumors, miRNA target genes, miRNA silencing,
Introduction: We have previously identified five upregulated and four downregulated miRNAs in small intestinal neuroendocrine tumor (SI-NET) tissue. We extended our analysis to serum samples of SI-NET patients to depict miRNAs functions.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author: Li S
Authors: Li S, Khan M, Caplin M, Öberg K, Meyer T,
Keywords: neuroendocrine tumors, serum miRNA expression, miRNA, target functions ,
Introduction: MicroRNAs (miRNAs), post-transcriptional regulators, function either as tumor suppressors or oncogenes. We recently identified five upregulated and four downregulated miRNAs in small intestinal neuroendocrine tumor (SI-NET) tissue. We then started new analysis on body fluids to detect tumor signatures using patients’ serum.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author:
Authors: Naboulsi R, Li S, Cui T, Öberg K, Giandomenico V,
Keywords: neuroendocrine tumors, serum miRNA expression, miRNA target functions,